R. Amram ben Diouane was born in Jerusalem. Later he moved to Hebron and, in 5523 (1743), was chosen by the rabbis of Hebron to be an envoy in Morocco with the mission to raise money for Yeshivot of the Holy Land. He founded a Talmud-Torah and Yeshiva where many disciples came to quench their thirst and study the source of his words.

His paternal affection created a strong bond between teacher and students. Through his rich and varied activities, R. Amram contributed to the rise and spread of Torah in all communities in Morocco. Rabbi Amram was also famous for his miracle and his blessings throughout all the cities of Moroccowherever the Jews sought to be freed from their misery. He was concerned for the welfare of everyone, so that his house was open to all who knocked at his door, with the hope that the Tzadik is their best defender to Our Father, The Holy Blessed be He. After ten years in Morocco, R. Amram felt great nostalgia for the Land of Israel. He interrupted his holy work, the students whom he had taught Torah having already become great scholars. When R. Amram arrived in Hebron, he befriended the Rabbis of the city, Rabbi Haim Bagoyo, and Rabbi Avraham Guidélia. Together they studied Torah, penetrating all its wonderful secrets, and climbing every day to higher levels of perfection in study and in the divine service. An unfortunate event was the cause of being forced to again take the pilgrim's staff and to return to Morocco.

At that time, Jews were not allowed to enter the Tomb of the Patriarchs. But for Rabbi Amram, this prohibition did not calm his burning desire to pray at the tomb of the patriarchs. He therefore dressed as an Arab, and without being noticed, entered the cellar with the rest of Muslims who were also praying. His face flooded with tears, he murmured prayers, begging the Creator of the world to precipitate the final issue. No one suspected that the "Muslim", so absorbed in his prayer, was a Jew. Suddenly, while Rabbi Amram was preparing to leave, one Arab recognized him. Immediately, he ran to the Pasha, and informed him of the offense. Rabbi Amram incurred a heavy penalty for this sacrilege. A servant of the Pasha, a friend Rabbi Amram, hurried to warn him that the Pasha intended to arrest him. In the middle of the night, Rabbi Amram accompanied by his youngest son, Rabbi Haim left his home. He feared to return to Jerusalem and neighboring countries since Turkish power spanned several countries. So R. Amram decided to return to Morocco. Upon his arrival in Fez, the inhabitants of the city welcomed him with honors, each fighting for the merit of hosting him. He was received by Rabbi Menache Ibn Denan, a community leader of Fez. It is said that Rabbi Menache had only daughters. Rabbi Amram advised him to appoint Fedin, which means we have done, i.e. we have finished childbearing girls. And so after this girl, Rabbi Menache than had boys. Shortly after his arrival in Fez, Rabbi Amram and his son Rabbi Haim toured every city of Morocco to propagate Torah. He arrived in Sefrou, and was hosted by the family Elbaz. This family had no children, and asked a blessing for a son. Rabbi Amram blessed them and promised that next year at this time, the woman would give birth to a son who would be a great scholar in the Torah. The blessing of the Tzadik was realized. The son who was born in the family Elbaz was named for the Tzadik: Amram. Subsequently the name of Rabbi Amram Sefrou Gaon was known as a scholar and in the Torah.

While Rabbi Amram was at the family of Sefrou Elbaz, Rabbi Haim his son fell seriously ill. The doctors gave him no chance to heal. Rabbi Amram prayed to the Creator of the world to take his soul to the place of that of his son. His son, Rabbi Haim’s illness was cured. They continued their trip in all cities in Morocco and came to Wazan, Rabbi Amram fell seriously ill. Shortly after he gave his soul to his Creator. The tomb of Rabbi Amram became a place of pilgrimage for all Jews of Morocco. Each year, on Lag Baomer, thousands of Jews came to Wazan for a pilgrimage to the tomb of the saint. It is said that many miracles performed on his tomb. Patients without hope of healing, healed, blind people found the view, reflected the dumb speak, the crippled were returning home on foot and infertile women children after having prayed at his tomb. It is said that a sergeant french had a son who was paralyzed after a serious illness. The sergeant had a Jewish friend, who advised him to take his son to the tomb of Rabbi Amram in Wazan. Initially, the sergeant was skeptical but then he promised that if a miracle occurs, and his son would is healed, he would build, with his own money, a road to facilitate access to the tomb of the Tzadik. The miracle occurred. As soon as his son approached the tomb of Rabbi Amram, he was healed. The happy father kept his promise and built a road to the tomb of Rabbi Amram. The great poet, Rabbi David Ben Hassin, composed a liturgical poem especially for Rabbi Amram that song is sung by all the Jews of Morocco on the day of its Hilloula.