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R. Cases was from a distinguished family with roots in Mantua. Hananiah wrote responsa, included in the responsa of his contemporaries, and an epistle to R. Nehemiah ben Baruch concerning musical harmony in the recitation of the priestly benediction (Birkat Kohanim), included in R. Nehemiah's Meliz u-Meliz (Venice, 1715). His most important works, however, are Kinat Soferim and Hok le-Yisrael.